Grainy head in tube size control and wound healing

Grainy head (grh), is a phylogenetically conserved transcription factor. In grh mutants, the apical epithelial cell membrane is overgrown resulting in overgrown airway tubes. Except for its developmental function, Grh emerged as a major regulator of epidermal wound healing in vertebrates and flies. A major focus of our work is the functional analysis Grh target genes, which we recently identified by ChIP-seq. We are exploring their function in epithelial wound healing and airway tube size control.

Last updated: November 25, 2011
Page editor: Magdalena Hernow

Tell a friend

Contacts

Cell Biology Per Ljungdahl, Phone: +46 8 16 41 01

Developmental Biology Christos Samakovlis, Phone: + 46 8 16 15 64

Immunology Marita Troye Blomberg, Phone: + 46 8 16 41 64

Physiology Barbara Cannon, Phone:+ 46 8 16 41 20

Imaging Facility, IFSU

Projects

Grainy head in tube size control and wound healing

Contacts

Imaging Facility, IFSU

Vacancies

Collaboration