Reference number: SU-465-0152-24

Deadline for applications: Sept 28, 2024

Stockholm University is a leading European university offering a multicultural environment in one of the world’s most dynamic capital cities. With more than 60,000 students and 5,000 staff, the University facilitates individual and societal development by providing top quality education that is tightly linked to its internationally recognized research programs. 

Research at the Department of Molecular Biosciences, The Wenner-Gren Institute (MBW) experimentally addresses fundamental problems in molecular cell biology, integrative biology, and infection and immunobiology. State-of-the art and advanced methodologies are applied in a professional research environment characterized by its well-established international profile. The institute has 30 research groups with a research staff of 200, of which 60 are PhD students. Read more about MBW at www.su.se/mbw. 

Project description

We are seeking a highly motivated and talented postdoctoral scientist to join the research groups of Ylva Engström and Marc Friedländer. The focus of this fellowship will be on the regulation of protein translation and stop codon readthrough (SCR). The primary objective is to generate comprehensive genome maps of SCR and to identify the cis- and trans-regulatory elements that control SCR in a temporal and spatial manner. This will be done by employing a combination of experimental and computational methods, including Ribo-Seq, RNA pull-down and mass spectrometry, reporter assays in cells and tissues, and computational sequence analyses. This implies to collaborate closely with our research teams in an interdisciplinary environment, which has expertise with the methods and approaches listed above. 

Qualification requirements 

The applicant should have a PhD in a field related to Molecular Biosciences with demonstrated expertise in molecular biology techniques, such as RNA-seq or Ribo-seq. Fluency in spoken and written English, as well as a strong track record of carrying out and finalizing research projects is mandatory. Prior experience with computational biology is a merit (e.g., ability to work in Linux environment, basic scripting), but the successful applicant will also receive extensive training and supervision to analyze the produced omics sequence data as part of the shared placement in the Friedländer team. 

For this application, the PhD degree should have been completed no more than three years before the deadline for applications. An older degree may be acceptable under special circumstances, which may involve sick leave, parental leave, clinical attachment, elected positions in trade unions, or similar. 

Terms of the scholarship 

This scholarship is enabled by funding from The Carl Tryggers Stiftelse and the terms of the scholarship are regulated by the foundation (https://www.carltryggersstiftelse.se/this-is-the-carl-trygger-foundation/). The scholarship is for full-time postdoctoral studies for two years (1+1). Start date in May or as per agreement. 

Additional information 

Further information about the project and about the conditions of this fellowship can be obtained from Ylva Engström: Phone +46-(0)8-164166, Email: ylva.engstrom@su.se or Marc Friedlander: + 46-(0)73 712 1558, Email: marc.friedlander@scilifelab.se